ASCP ASCP-MLT : MEDICAL LABORATORY TECHNICIAN - MLT(ASCP)

  • Exam Code: ASCP-MLT
  • Exam Name: MEDICAL LABORATORY TECHNICIAN - MLT(ASCP)
  • Updated: Sep 03, 2026     Q & A: 562 Questions and Answers

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ASCP ASCP-MLT Exam Syllabus Topics:

SectionObjectives
Laboratory Operations- Quality and safety in the clinical lab
  • 1. Laboratory safety and regulations
    • 2. Quality control and assurance
      Clinical Chemistry- Metabolic and analytical testing
      • 1. Endocrine and metabolic panels
        • 2. Enzymes and electrolytes
          Urinalysis and Body Fluids- Fluid analysis and interpretation
          • 1. CSF and other body fluids
            • 2. Urine chemical and microscopic examination
              Hematology- Blood cell analysis and disorders
              • 1. Anemias and leukemias overview
                • 2. CBC and differential interpretation
                  Blood Banking / Immunohematology- Blood group systems and antibody identification
                  • 1. ABO and Rh systems
                    • 2. Crossmatching procedures
                      Microbiology- Clinical microbiological techniques
                      • 1. Bacteriology and organism identification
                        • 2. Culture and sensitivity testing

                          ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

                          Question 1

                          If all newborns were tested, many positive DATs due to ABO incompatibility would be detected that are of no clinical significance.
                          Although many laboratories test infants born to group O Rh positive females due to the higher risk of ABO HDFN when the mother is group O, testing such infants is optional provided there is appropriate monitoring and follow-up for hyperbilirubinemia.
                          Blood Bank
                          Not performing direct antiglobulin tests (DATs) on newborns born to group O Rh positive mothers is acceptable good practice, providing there is appropriate surveillance and follow-up to detect hyperbilirubinemia.

                          A. true
                          B. false


                          Question 2

                          What is the first thing a phlebotomist should do in the event of an accidental needle stick?

                          A. go to the employee health service and get a tetanus booster
                          B. check the patient's medical records
                          C. leave the area so that the patient does not notice the injury
                          D. decontaminate the site and fill out an incident report


                          Question 3

                          Gamma globulin (anti-D) is given to Rh-negative mothers to prevent any D antibody production, which could cause harmful effects in future pregnancies with an Rh-positive fetus. The administered anti-D will bind fetal Rh-positive cells that may come from the fetus in vivo; therefore the mother will not produce anti-D herself, preventing sensitization.
                          A solution of gamma globulins containing anti-Rh (D) is given to an Rh (D) negative mother to:

                          A. Prevent greater antibody response in a previously sensitized mother
                          B. Neutralize any natural maternal antibodies present
                          C. Prevent fetal cells from initially sensitizing the mother
                          D. Neutralize any of the child's antibody that may have passed the placental barrier


                          Question 4

                          Serum amylase and lipase levels may be slightly elevated in chronic pancreatitis, but not diagnostic enough to predict chronic pancreatitis; wheras high levels are found only during acute pancreatitis episodes. In the later stages of chronic pancreatitis, normal to decreased levels of amylase and lipase are caused by the gradual inability of the pancreas to secrete the enzyme All of the statements below regarding amylase and lipase in pancreatitis are TRUE EXCEPT:

                          A. Urinary amylase: creatinine ratio is the most sensitive test for acute pancreatitis.
                          B. Serum lipase peaks at 24 hours after an episode of acute pancreatitis and remains high for 7-8 days.
                          C. Amylase and lipase are as predictive in chronic as in acute pancreatitis.
                          D. Diagnosis sensitivity is increased by assaying both amylase and lipase.


                          Question 5

                          The deposition of plaques containing cholesterol and lipids on the innermost layer of the walls of large and medium-sized arteries is the defintion of atherosclerosis.
                          Arteriosclerosis is a more general term that describes a thickening and loss of elasticity of the walls of the arteries (hardening of the arteries). Atherosclerosis is a type of arteriosclerosis but is not synonymous with it.
                          Atherosclerosis is not the most common outcome for risk marker studies because it can be hard to measure.
                          Infarcts, cardiac procedures, death, and 'events' are more common. Most humans have visible or measureable atherosclerosis by early middle age.
                          Chemistry
                          Which of the following is true concerning atherosclerosis?

                          A. Most humans do not have significant atherosclerosis.
                          B. Atherosclerosis is the main outcome that is assessed in risk marker studies.
                          C. Atherosclerosis is the deposition of plaques containing cholesterol and lipids on the innermost layer of the walls of large and medium-sized arteries.
                          D. Atherosclerosis is the same as arteriosclerosis.


                          Solutions:

                          Question 1
                          Answer: A
                          Question 2
                          Answer: D
                          Question 3
                          Answer: C
                          Question 4
                          Answer: C
                          Question 5
                          Answer: C

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